Long-term use of metformin lowers vitamin B12 levels, so it should be taken with vitamin B12.For anti-aging purposes, 1000 mg of metformin and vitamin B12 were taken together for 3 weeks. Taking 1,000mg at a time after eating in the evening and resting was less likely to lower the basal metabolic rate than when eating at breakfast or lunch.As a result, I felt good because I seemed to sleep bette..
